The genome of every organism defines its function in health and disease. Through multiple steps, the information encoded by the genes is converted to functional units that orchestrate the organism activity. Our research focuses on the molecular mechanisms that underlay these steps of gene expression. Specifically, we are interested in steps of mRNA localization and translation regulation which emerge as key for fine tuning of cellular function. We apply various methods, including electron microscopy, biochemical purification, molecular biology, in vivo fluorescent imaging and functional genomics to understand how mRNAs are regulated, what are the RNA sequences that are important for regulation and which proteins are involved.
More details can be found in the Research section.